Following up on his groundbreaking Counterbalance Study from 2015, Professor Roy Taylor from Newcastle University has now revealed more of what he learned and how he demonstrated the reversal of Type 2 diabetes with a low calorie diet. He says his research confirms his Twin Cycle Hypothesis that Type 2 diabetes, a condition that affects nearly 30 million people in the U.S., is caused by too much fat in the liver and pancreas.
In his study he put 11 people who had developed diabetes later in life on an extremely restricted liquid diet of just 600 calories a day plus 200 calories of non-starchy vegetables. After just one week, study participants had their pre-breakfast blood sugar levels return to normal. An MRI scan of the pancreas revealed fat levels had returned from an elevated level to normal (from around eight percent to six percent) and the pancreas regained the ability to make insulin and blood sugar levels after meals steadily improved.
The trial lasted for eight weeks and participants were tested again three months after the study was complete. During those three months they returned to unmonitored eating after receiving counsel on portion sizes and healthy choices. Of the 10 volunteers who were re-tested, seven remained free of diabetes.
“By studying the underlying mechanisms we have been able to demonstrate the simplicity of type 2 diabetes,” Taylor said. He explains that excess calories lead to excess fat in the liver. As a result, the liver responds poorly to insulin and produces too much glucose. That excess fat in the liver is passed on to the pancreas, causing the insulin producing cells to fail.
“The good news for people with Type 2 diabetes is that our work shows that even if you have had the condition for 10 years, you are likely to be able to reverse it by moving that all important tiny amount of fat out of the pancreas. At present, this can only be done through substantial weight loss,” Taylor added.
“We believe this shows that Type 2 diabetes is all about energy balance in the body,” Taylor explained. “If you are eating more than you burn, then the excess is stored in the liver and pancreas as fat which can lead to Type 2 diabetes in some people. What we need to examine further is why some people are more susceptible to developing diabetes than others.”
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